At Graze, a Madison, WI, restaurant that sources its ingredients from small regional farms, the grilled cheese sandwich ($10) combines Hook’s Cheddar, tomato and caramelized onion on a Pullman loaf with whole-grain mustard.

In San Francisco, The Italian Job ($5.95) is one of the four grilled cheese sandwich selections at The Melt. It’s a combination of fontina and provolone cheeses with grilled mushrooms on spicy garlic bread.

Melt Bar and Grilled offers creative grilled cheese sandwiches, including the Mighty Macaroni ($12.50), at its seven locations in Ohio. The sandwich is filled with battered, deep-fried macaroni and cheese and layered with cheddar cheese sauce and a favorite melted cheese.

Tom and Chee—a grilled cheese sandwich and tomato soup concept—offers sandwiches such as the Armagoetta ($7.95) at its locations across the U.S. This crunchy grilled cheese combination features goetta, a German-style meat and grain breakfast sausage popular in Cincinnati, the brand’s flagship location. The sandwich also includes cherry peppers, fried onions, sweet hot mustard and pepper jack cheese on sourdough and pumpernickel rye.

This sandwich featuring Swiss, aged Cheddar cheeses, wood-roasted red bell pepper and hickory smoked bacon on Texas toast ($7.95) is a signature at The Old Fashioned, a Wisconsin-themed, retro-inspired tavern in Madison.